Acid Hypoclorous (HOCl)

Hypochlorous acid (HOCl) is produced naturally by white blood cells in the human body as a first line of defense in the immune response. HOCl is a powerful oxidant that is effective against a broad spectrum of pathogens, including bacteria, viruses, fungi, and spores. Despite its strong antimicrobial properties, pure HOCl is completely safe for human tissues and the environment.

HISTORY

Contrary to the popular belief that HOCl is a recent discovery, it actually boasts a long and well-established history of research and applications worldwide.

1834

Discovered in 1834 by French chemist Antoine Jérôme Balard, …

1915

.. notably employed as a wound antiseptic during World War I.

1940

…and its use extended to hospitals in London to control the airborne spread of pathogens.

1950

…applications in agriculture…

1970-1980

…applications in agriculture, and more recently, it has been proposed for use in drinking water disinfection and wastewater treatment.

2000

…and it has been approved for use as a disinfectant in the food industry in Japan and the United States.

2015

…and it has been approved for use as a disinfectant in the food industry in Japan and the United States. HOCl is considered the ‘most active chlorine species with strong bactericidal activity against a wide range of microorganisms.’ It is authorized for commercial use in various products for disinfection and wound treatment on the human body.

2020

…and it has been approved for use as a disinfectant in the food industry in Japan and the United States. HOCl is considered the ‘most active chlorine species with strong bactericidal activity against a wide range of microorganisms.’ It is authorized for commercial use in various products for disinfection and wound treatment on the human body, and is listed by the EPA on List N for use against SARS-CoV-2.

CURRENTLY

…and is listed by the EPA on List N for use against SARS-CoV-2. HOCl has been extensively researched by institutions in over 50 countries, with more than 2,600 studies focused on its antimicrobial efficacy and over 3,000 studies exploring its wound care applications.

Benefits of HOCl

    Hypochlorous acid (HOCl) offers a range of benefits, particularly in healthcare and sanitation applications:

    • Powerful Antimicrobial Action: HOCl is a highly effective disinfectant, capable of eliminating a broad spectrum of microorganisms, including bacteria, viruses, fungi, and spores. This makes it a valuable tool for infection control and prevention.
    • Anti-Inflammatory Properties: HOCl has been shown to possess anti-inflammatory properties, helping to reduce redness, swelling, and pain associated with tissue damage or infection. It can also help to break down biofilms, which are communities of microorganisms that can be difficult to eradicate with traditional disinfectants.
    • Wound Healing Support: HOCl can promote wound healing by reducing inflammation, fighting infection, and stimulating tissue regeneration. It is safe for use on various types of wounds, including chronic wounds and burns.
    • No Antimicrobial Resistance: Unlike some antibiotics and disinfectants, HOCl does not contribute to the development of antimicrobial resistance. This makes it a sustainable solution for long-term infection control.
    • Safe for Long-Term Use: HOCl is well-tolerated and can be used safely over extended periods, even on sensitive tissues. This is particularly important for chronic conditions or situations requiring ongoing disinfection.

    In addition to these benefits, HOCl is also environmentally friendly and non-toxic, making it a safe and sustainable alternative to traditional disinfectants.

APPLICATIONS

With its broad spectrum of antimicrobial activity yet safe and biocompatible nature, HOCl does not irritate the skin, mucous membranes, bones, cartilage, and muscles. HOCl also does not cause side effects with prolonged use. Therefore, it is widely used in medicine.

Below are the applications of HOCl and related scientific studies in a number of specialties:

SOME SCIENTIFIC STUDIES

SOME SCIENTIFIC STUDIES (Click on the link to view scientific reports)

APPLICATIONS

With its broad spectrum of antimicrobial activity yet safe and biocompatible nature, HOCl does not irritate the skin, mucous membranes, bones, cartilage, and muscles. HOCl also does not cause side effects with prolonged use. Therefore, it is widely used in medicine.

Below are the applications of HOCl and related scientific studies in a number of specialties:

  1. Surface and instrument disinfection
  2. Wound care
  3. Hands
  4. Eyes
  5. Nose
  6. Throat
  7. Burns 1 & 2

APPLICATIONS

With its broad spectrum of antimicrobial activity yet safe and biocompatible nature, HOCl does not irritate the skin, mucous membranes, bones, cartilage, and muscles. HOCl also does not cause side effects with prolonged use. Therefore, it is widely used in medicine.

Below are the applications of HOCl and related scientific studies in a number of specialties:

  1. Hand disinfection
  2. Mouth disinfection before treatment
  3. Endodontics
  4. Periodontology
  5. Daily mouthwash
  6. Air disinfection spray
  1. Multipurpose disinfection
  2. Food disinfection